Put as few clicks between your visitor and the information they have come for as possible.
The more you force your visitors to click and click again through your website, the more likely they'll leave. Or they'll get annoyed, or not view as much of your content.
Is your home page a splash page (a page with no meaningful information on it, that simply "welcomes" visitors to the site, along with an "Enter Site" link)? If so, get rid of it.
If someone takes the effort to visit your website, give them your website right away! Give them the information they came for. Tell them what you do and who you do it for, right up front.
Importantly, a splash page is almost useless for search engine optimisation as well. Google also wants to know what you do, and they can't read images.. just text.